I think that we often forget that we are in charge of our own lives. When people try to manipulate you for their own agenda, the manipulation only works if we let them. So many people, especially our families, use guilt and blame to manipulate us into doing their bidding.
Today, when someone tries manipulation on you, see if it works if you say, "That does not work with my immediate plans. I am sorry. Here is my suggestion." Use discretion when saying this. It may not work with a boss or co-worker because you may need to come up with a different phrase for them. Still, all of us need to find a way to live our lives and go about our daily tasks with our own agenda at the top of what needs to happen.